Universidad del Pais Vasco. UPV/EHU
Responsable: Jose Luis Pedraz Muñoz
Componentes:
Jose Luis Pedraz knppemuj@vc.ehu.es
Facultad de Farmacia. Paseo de la Universidad nº 7. 01006 Vitoria.
Teléfono: 945-013091 Fax: 945-013040
www.vc.ehu.es/castellano/paginas/prin_c.htm
Del Pozo-Rodríguez A, Delgado D, Solinís MA, Gascón AR, Pedraz JL.
Solid lipid nanoparticles for retinal gene therapy: Transfection and intracellular trafficking in RPE cells.
Int J Pharm. 2008 Apr 22.
doi:10.1016/j.ijpharm.2008.04.023. En prensa.
D Otaegui, AR Gascón, A Zubia, F P. Cossío, JL Pedraz.
Development and validation of a liquid chromatography–tandem mass spectrometry for the determination of Kendine 91, a novel histone deacetylase inhibitor, in mice plasma and tissues: Application to a pharmacokinetic study.
Journal of Chromatography B 287:109-116 (2008).
Isla A, Gascón AR, Trocóniz IF, Bueno L, Solinís MA, Maynar J, Sánchez-Izquierdo JA, Pedraz JL.
Population pharmacokinetics of meropenem in critically ill patients undergoing continuous renal replacement therapy.
Clin Pharmacokinet. 47: 173-80 (2008).
Isla A, Canut A, Gascón AR, Labora A, Ardanza-Trevijano B, Solinís MA, Pedraz JL.
Pharmacokinetic/pharmacodynamic evaluation of antimicrobial treatments of orofacial odontogenic infections.
Clin Pharmacokinet 44:305-16 (2005).
Igartua M., Hernández R.M., Rosas J.E., Patarroyo M.E., Pedraz JL Gamma-irradiation effects on biopharmaceutical properties of PLGA microspheres loaded with SPf66 synthetic vaccine.
European Journal of Pharmaceutics and Biopharmaceutics 69: 519-526 (2008)
Mata E., Montero A., Hernández R.M., Igartua M., Corradin G., Pedraz, J.L.Adjuvant activity of polymer microparticles and Montanide ISA 720 on immune responses to Plasmodium falciparum MSP2 long synthetic peptides in mice.Vaccine 25: 877-885 (2006)
Montero A., Hernández R.M., Igartua M.,Rosas J.E., Patarroyo M.E., Pedraz J.L.
Enhancing inmunogenicity and reducing dose of microparticulate synthetic vaccines: single intradermal administration.
Pharmaceutical Research 21: 121-126 (2004)
Murua A, De Castro M., Orive G., Hernández RM, Pedraz JL In vitro characterization and in vivo functionality of EPO-secreting cells immobilized in alginate-PLL-alginate microcapsules.
Biomacromolecules 8: 3302-3307 (2007)
Ponce S., Orive G., Hernández R.M., Gascón A.R., Pedraz J.L., Haan B.J., Faas M.M., De Vos P. Chemistry and the biologic response against immunoisolating alginate-polycation capsules of different composition.
Biomaterials 27: 4831-4839 (2006)
Ochoa L., Igartua M., Hernández R.M, Gascón A.R., Pedraz J.L. Preparation of sustained release hydrophilic matrices by melt granulation in a hig-shear mixer. Journal of Pharmacy and
Pharmaceutical Sciences 8:132-140 (2005).